of the Urals

Russian Journal of Agricultural Research

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for Affairs of the Press, Television and Radio Broadcasting and Mass Communication Media.
Registration certificate: PI number 77-12831 on May 31, 2002
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ISSN 1997 - 4868 (Print)

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Journal is included in the list of VAK (from 25.09.2017), No. 291

ISSN 2307-0005 (Online)
Key title: Agrarnyj vestnik Urala (Online)
Abbreviated key title: Agrar. vestn. Urala (Online)

Аграрный вестник Урала № 13 (167) 2017

Биология и биотехнологии

Дроздова Л. И. доктор ветеринарных наук, профессор, заслуженный деятель науки РФ Уральский государственный аграрный университет

Садовников Н. В. доктор ветеринарных наук, профессор Уральский государственный аграрный университет

Реутова Е. А. кандидат ветеринарных наук, доцент Новосибирский государственный аграрный университет

УДК:УДК 619.576.31:599.323.4


 Thepaper presents material on the manifestation of the morphological reaction ofthe liver of piglets after the application of nucleic nature “Westin” in thesystem “мother-fetus”.The liver is one of the main organs that support homeostasis in mammals,participates in all kinds of metabolism and is the most suitable object forstudying general and particular problems of the influence of drugs. Duringpregnancy, as well as in the period of early postnatal development, changes inthe liver can occur that are necessary for energy supply and maintenance of theorganism’s vitality. The studies were performed on sows oflarge white breed and the piglets from 10 daily to 7 months of age. Forhistological examination samples of the liver of the piglets were recorded inthe 10–12 % solution of neutral formalin was poured into the wax, preparing thesections with thickness of 5–7 µm and stained by classical methods ofmorphological research. In sections of liver was carried out morphometricstudies. In the liver of piglets of the experimental group noted the change ofimmunomorphological reactions in the form of the accumulation of lymphoid cellsin the region of the triads by the type of follicle. A pronounced symptom ofthe liver of pigs of the control group was the growth of connective tissuecapsule and region of the triad due to the increase in the number andhypertrophy of cells reticulohistiocytoma system. Histochemical analysis ofhepatocytes of the liver of newborn piglets, showed lipid inclusions and thepresence of uniformly and densely arranged in the Central portions of the cellsof granules of glycogen both in the centre and the periphery of the lobules,the presence of intense staining for RNA, the intensity of such staining in thecytoplasm of hepatocytes of piglets of the control group was visually somewhatreduced and represented by small granules. It is shown a positive effect oftest drug on the morphological structure of the liver of pigs and the formationof adaptive reactions of the organism. The drug is the “Westin” with theintroduction of the system “мother-fetus” in the later stages of fruiting, has apositive influence on the content of glycogen and RNA in the hepatocytes of theliver of pigs that is characterized by a high level of energy and plasticprocesses.


Keywords: adaptation, immunocorrection, morphologic reaction, liver, hepatocyte, piglets, “mother-fetus” system, nucleic preparation.


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