Agrarian
Bulletin
of the Urals

Russian Journal of Agricultural Research

The publication is registered by the Ministry of the Russian Federation
for Affairs of the Press, Television and Radio Broadcasting and Mass Communication Media.
Registration certificate: PI number 77-12831 on May 31, 2002
Subscription index in catalog «Russian Press» - 16356
ISSN 1997 - 4868 (Print)

The Journal is included in the list of the leading peer-reviewed scientific journals and publications, which should be published by the main results of theses for the degree of doctor and Ph.D.
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Journal is included in the list of VAK (from 25.09.2017), No. 291

ISSN 2307-0005 (Online)
Key title: Agrarnyj vestnik Urala (Online)
Abbreviated key title: Agrar. vestn. Urala (Online)

Аграрный вестник Урала № 08 (126) 2014

Ветеринария

Слепцов Е. С. доктор ветеринарных наук, профессор Якутский научно-исследовательский институт сельского хозяйства

Винокуров Н.В. кандидат ветеринарных наук, старший научный сотрудник

Захарова О.И. аспирант Якутский научно-исследовательский институт сельского хозяйства

Устинцева Ю.Ю. кандидат ветеринарных наук, научный сотрудник Якутский научно-исследовательский институт сельского хозяйства

Малышева И.А. младший научный сотрудник Якутский научно-исследовательский институт сельского хозяйства

УДК:619:579.841.93:616-084:616-079.3

IMMUNOGENICITY OF THE VACCINE FROM STRAINS B.ABORTUS 19 AND 82, B.SUIS 61 FOR REINDEER IN DIFFERENT METHODS OF ADMINISTRATION

Researches carried out on the reindeer basis № 6 experimental industrial enterprise “Yuchyugeyskoe” in Oymyakon region of the Republic of Sakha (Yakutia). In conducting research shows the best concentration of vaccine doses strains B.abortus 19, B.abortus 82 and 61 when administered B.suis. It has been established that strain B.abortus 19 of diluted concentrations when administered 10 milliard m. c. develops high immunogenicity of 100 %. The same results were obtained by immunization of deer by vaccine from strain B.suis 61 (100 % immune). In groups of animals vaccinated by immune strain 82 66.7 % appeared as two animals vaccinated subcutaneously and conjunctiva penetration was set immunity infecting isolated strain 1330 B.suis lymph nodes. The results of studies of vaccines depend on the concentration of the microbial cells on the dose and method of administration. Terms of appearance and persistence of antibody titers are directly dependent on the vaccine. Early appearance, high level and long-term preservation of post-vaccination antibody marked with subcutaneous method of administration of the vaccine and low antibody titers and their rapid extinction when administered orally. Application of the vaccine from strain B.suis 61 is suitable for widespread practical use in reindeer brucellosis.

Keywords:

brucellosis, infection process, immunity, strain, epizootic process, vaccine, reindeer


References:

1. Sleptsov E. S., Vinokurov N. V., Evgrafov G. G. Properties of the vaccine from strain B.abortus 82 and B.abortus 75/79-AB

in reindeer organism // Achievement of science and technology AIC. 2013. № 4. P. 72–73.

2. Sleptsov E. S., Vinokurov N. V., Fedorov V. I., Evgrafov G. G. Immunological reactivity of reindeer organism after reimmunization

by vaccines from strains B.abortus 82 and B.abortus 75/79-АВ // Agrarian bulletin of the Urals. 2011. № 4 (83). P. 27.

3. Khotch A. A., Sleptsov E. S. Specific prevention of reindeer brucellosis. Reindeer brucellosis in Yakutia. Yakutsk, 2001. P. 87–89.


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